Every Time I Die, Set Your Goals, Cancer Bats For European Tour

Hot off the announcement that they'll be releasing their sixth album 'Ex Lives' in March, Every Time I Die have announced a massive European tour.

With support coming from the likes of Set Your Goals, Cancer Bats and Make Do And Mend, the four band bill will hit up an extensive array of venues throughout mainland Europe.

MAY
01 Cologne Underground, Germany
02 Frankfurt Batschkapp, Germany
03 Stuttgart Universum, Germany
04 Zurich Abart, Switzerland)
05 Muinch Backstage Halle, Germany
06 Vienna Szene, Austria
08 Bratislava Randall Club, Slovakia
09 Prague Rock Caf?, Czech Republic
10 Schweinfurt Stattbahnhof, Germany
11 BEerlin Columbia Club, Germany
12 Copenhagen Pumphuset, Denmark
13 Stockholm Klubben, Sweden
14 Gothenburg Sticky Fingers, Sweden
15 Aarhus Train, Denmark
16 Hamburg Knust, Germany
17 Bremen Lagerhaus, Germany
18 Hannover Faust, Germany
19 Eindhoven Dynamo, Holland
21 Moscow Plan B, Russia
22 St Peterburg Arktika, Russia
23 Helsinki Nosturi, Finland

Source: http://www.thisisfakediy.co.uk/articles/news/every-time-i-die-set-your-goals-cancer-bats-for-european-tour

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Saudi Arabia's automotive aspirations | GantDaily.com

January 8, 2012 at 1:57 PM by AHN ? ?

The Media Line Staff

Riyadh, Saudi Arabia Rob L. Wagner (The Media ? Not content with oil, the kingdom wants to make cars as well; skeptics abound.

Two years ago, the Saudi Arabian government announced with great fanfare ? and was met with some skepticism ? plans to manufacture automobile parts by 2013 and assemble cars by 2021. King Saud University engineering students, who designed an economical sport utility vehicle called the Ghazel, bolstered those plans with a tangible vehicle ready for production.

Saudi economic analysts are optimistic that automobile manufacturing in the kingdom will help reduce the economy?s reliance on oil exports. Yet roadblocks persist. Already the goal to manufacture car parts next year is in jeopardy as infrastructure and a trained labor pool are not in place. It begs the question of whether Saudi Arabia can pull off a massive undertaking within its stated timetable or even come close to it.

?It?s not realistic,? Asaad Jawhar, an economics analyst and professor at Jeddah?s King Abdulaziz University, told The Media Line. Jawhar says manufacturing automobile parts is more likely to get underway within five years.

Saudis love their cars, purchasing an estimated 800,000 in 2011 with an expected 1 million cars to be bought annually by 2020. The Petroleum and Minerals Ministry and the Commerce and Industry Ministry are investing in research and development, design, vehicle assembly and infrastructure to create enough exports to help the kingdom wean itself from oil revenues.

The ministries initiated the National Industrial Clusters Development Program to help achieve those diversification goals by focusing on five industries: automobile manufacturing, solar energy, plastics, home appliances and minerals processing.

The most ambitious challenge is building cars.

Fayez Al-Sharef, chemical project director for Saudi Aramco, told Bloomberg News in October that he expects the nascent Saudi automotive industry to eventually create 100,000 jobs and produce a half-million cars every year.

If the vision of self-sufficiency through diversification sounds familiar, it?s because Saudi Arabia has been down that road before and failed.

Saudi Arabia has been looking since the 1970s for the magic export product that will minimize its dependency on oil. The government implemented an ambitious plan to develop its agricultural industry to become self-sustaining and provide every Saudi household with food grown within its borders.

Production of wheat and rice rose steadily, but so did the expensive proposition of building irrigation systems to bring groundwater to the crops. Between 1984 and 2000, Saudi Arabia spent an astronomical $83.6 billion to irrigate crops and build agricultural infrastructure. The project cost more than twice it would have to import foodstuff, according to the School of Oriental and African Studies at King?s College London.

However, the 1991 Gulf War put a severe strain on the Saudi budget and groundwater ? its availability in the desert always an issue ? was increasingly difficult to bring to the surface. Efforts to maintain irrigation of 1.12 million hectares, the level irrigated in 2000, is almost an impossible task. The project could not be sustained.

?The most important thing was not to rely heavily on oil, but to rely on agriculture and they (Saudi government) failed in agriculture,? Jawhar says. ?And now they are trying to find another way of transforming technology.?

There are signs that creating an automotive industry could work. During the third quarter of 2011, non-oil exports rose by 34 percent, mostly in petrochemicals and plastics, according to the Saudi General Statistics Department. China was the biggest consumer of these products.

Didier J. Vigouroux, vice-president of the Automotive Cluster for the National Industrial Clusters Development Program, told The Media Line that a Saudi automotive industry is capable of matching petrochemicals and plastics as viable exports.

?No one is thinking of giving up oil and gas, but to diversify from oil and gas,? Vigouroux says. ?And petrochemicals are a logical continuation. New industries like automobile manufacturing would target the success of petrochemicals and plastics as a goal.?

The brightening picture in exports lays the foundation for developing parts manufacturing plants and ultimately automotive assembly. Isuzu Motors Ltd. has an assembly plant in Dammam for medium- and heavy-duty trucks. The plant is expected to begin this year to produce about 25,000 vehicles annually for export to Asia.

Vigouroux says any timetable to bring other automobile assembly plants online is flexible.

?The only true assembly plant project in Saudi Arabia is the Isuzu plant, but as far as developing other plants we are still talking to certain companies,? he says.

Following its unveiling of the Ghazal sport utility vehicle, King Saud University inked an agreement with the South Korean engineering company Digm Automotive Technology to develop a car priced under $10,000. Saudi Arabia would export the car to neighboring Gulf countries and North Africa.

Jawhar says that producing inexpensive cars makes sense. ?Saudi Arabia should approach this step-by-step like Hyundai. They can succeed if they model after Korea. Korea produced small and bad cars at first, but is now doing well,? he says. ?By first producing [cheap] cars efficiently, they then build an institution.?

He notes, however, that exporting the Ghazal, or a similar inexpensive automobile, would not be competitive in foreign markets, but sell better domestically. ?Perhaps there?s a market in Africa, but even there I?m not sure.?

However, a slow start to get the fledgling industry out of the gate may not only scuttle the 2021 timetable for automobile production but also doom Saudi Arabia?s diversification plans.

While the Saudi government is financing production and logistics facilities through 20-year loans in the remote regions of Najran and Tabuk, the question remains whether employers can find competent Saudi labor. The government?s Nitaqat program requires that companies with more than 3,000 employees must employ Saudis for 30 percent of its workforce.

A Saudi engineering consultant, who asked not to be identified because he is not authorized to speak for his client, told The Media Line that it would be difficult to fill factory jobs with Saudis.

?With Nitaqat, assembly plants will have to fill unskilled labor positions with Saudis and I don?t see that happening,? he says. ?Which brings us back to how we always do things, and that?s hiring cheap foreign labor.?

Jawhar says finding Saudis in the skilled labor market is another story. ?The world doesn?t know that Saudis are learning fast,? he says. ?Saudis between 20- and 25-years-old with engineering education will be producing great cars with high technology 20 years from now.?

Vigouroux agrees. ?The right perspective to put on diversification is the significant desire to create employment for young Saudis coming out of universities,? he says. ?This means creating new curriculum and the right kinds of training and work ethic.?

But Vigouroux acknowledged that for 2012 Saudi Arabia?s automotive manufacturing infrastructure is minimal, although the know-how for developing automotive zones is available. ?We are addressing investment issues and there some impressive botanical parks in Yanbu and Jubail where there is already an expertise for mapping and running industrial cities.?

The key to overcoming infrastructure and labor issues is better cooperation between agencies. Jawhar observed that a successful automotive industry depends on two groups that historically have done a poor job developing marketable exports: the government and private business.

?If the government heads this they will fail and the private sector has not taken [automotive manufacturing] seriously,? Jawhar says. ?It?s a matter of trust between the two sectors that determines the outcome.?

Article ? AHN ? All Rights Reserved

---

Source: http://gantdaily.com/2012/01/08/saudi-arabias-automotive-aspirations/

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NVIDIA announces DirectTouch technology for Tegra 3 tablets, promises a smoother touch experience

You'd think that with Tegra 3 shipping in the Transformer Prime and all, we'd know everything there is to know about the new SoC. Apparently not. NVIDIA just announced DirectTouch, a technology exclusive to its Tegra 3 platform that uses that bonus fifth core for to improve touch detection. So what does a low-power core have to do with the touch experience, you say? Essentially, what's going on is NVIDIA's PRISM Display technology separates color and backlight intensity to save battery life while preserving fidelity. In a demo, the technology looked mighty smooth, though we'll need to get hands-on ourselves and see the technology in action for more than five seconds before we can weigh in on its utility.

Billy Steele contributed to this report.

NVIDIA announces DirectTouch technology for Tegra 3 tablets, promises a smoother touch experience originally appeared on Engadget on Mon, 09 Jan 2012 19:46:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/01/09/nvidia-announces-directtouch-technology-for-tegra-3-tablets-pro/

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In elections, jobless trend matters more than rate (AP)

WASHINGTON ? Unemployment is higher than it's been going into any election year since World War II.

But history shows that won't necessarily stop President Barack Obama from reclaiming the White House.

In a presidential election year, the unemployment trend can be more important to an incumbent's chances than the unemployment rate.

Going back to 1956 no incumbent president has lost when unemployment fell over the two years leading up to the election. And none has won when it rose.

The picture is similar in the 12 months before presidential elections: Only one of nine incumbent presidents (Gerald Ford in 1976) lost when unemployment fell over that year, and only one (Dwight Eisenhower in 1956) was re-elected when it rose.

Those precedents bode well for Obama. Unemployment was 9.8 percent in November 2010, two years before voters decide whether Obama gets to stay in the White House. It was down to 8.7 percent in November 2011, a year before the vote. It fell to 8.5 percent in December and is expected to fall further by Election Day.

Even so, the unemployment rate is still at recession levels. And former Massachusetts Gov. Mitt Romney, who is contending with other Republican candidates to challenge Obama in November, has made the weak economy the centerpiece of his campaign.

In a statement Friday, Romney said Obama's policies "have slowed the recovery and created misery for 24 million Americans who are unemployed, or stuck in part-time jobs when what they really want is full-time work."

An Associated Press-GfK poll of American adults last month found that 60 percent of American adults disapprove of Obama's performance on economic issues.

Obama can take comfort in President Ronald Reagan's experience. In November 1982, the economy was in the last month of a deep recession, and unemployment was 10.8 percent, the highest since the Great Depression. A year later, unemployment was down to 8.5 percent. By November 1984, it was still a relatively high 7.2 percent, but the downward trend was unmistakable. Reagan was re-elected that month in a 59-41 percent landslide.

"A sense that things are on the mend is really important to people," says Andrew Kohut, president of the Pew Research Center. Three examples:

? President Richard Nixon got a boost from falling unemployment, which dropped from 5.9 percent in November 1970 to 5.3 percent when voters went to the polls in November 1972.

? President Jimmy Carter was hurt by rising unemployment ? from 5.9 percent in November 1978 to 7.5 percent in November 1980.

? President George H.W. Bush, who seemed invincible after the U.S. drove Saddam Hussein's Iraqi forces out of Kuwait in early 1991, wound up losing in November 1992. The unemployment rate was 7.4 percent that month, up from 6.2 percent two years earlier.

The trend holds up even when the changes in unemployment are slight. President Bill Clinton was re-elected handily even though the unemployment rate was only 0.2 percentage points lower in November 1996 than it had been two years earlier and was the same as it had been a year before.

Under Obama, unemployment peaked at 10 percent in October 2009, nine months into his presidency, before it began coming down in fits and starts. Along the way it stayed above 9 percent for 21 straight months.

But unemployment has now dropped four months in a row. And the economy added 1.6 million jobs in 2011, the most since 2006.

Of course, unemployment isn't everything.

Obama's prospects could be changed by the strengths or weaknesses of whoever emerges as his Republican opponent or by a triumph or setback in foreign policy, perhaps in Afghanistan or the Middle East.

Eisenhower no doubt benefited from having an opponent, the high-brow former Illinois Gov. Adlai Stevenson, who had trouble connecting with ordinary voters. Ford may have been sunk by his unpopular decision to pardon former President Nixon. President Jimmy Carter's prospects were surely dimmed by the lengthy hostage crisis in Iran ? and a failed attempt to end it with a military rescue.

The third-party candidacy of billionaire Ross Perot ? not just an increase in unemployment ? may have torpedoed President George H.W. Bush's re-election campaign in 1992 by dividing his supporters and giving an edge to challenger Clinton.

And there's no guarantee that unemployment will continue to slide through Election Day. "We've seen this before ... periods when it seemed like things were getting better only to see them grind to a halt," says John Challenger, CEO of the staffing company Challenger, Gray & Christmas. "I'm not yet convinced."

Americans who have given up looking for work don't count as unemployed in the official tally. But if they get more optimistic, they might re-enter the job market and join the ranks of the officially unemployed, pushing the rate back up, says Republican strategist Rich Galen.

Galen says what matters is how the economy looks in late summer when undecided voters start making up their minds. "What people perceive in August is what they take to the polls with them."

Three dozen economists surveyed by The Associated Press in December see an 18 percent chance that Europe's debt crisis will cause the U.S. economy to slip back into recession. If 2012 brings a recession, Obama would surely lose, writes Yale University's Ray Fair, who feeds economic forecasts into a computer model to predict elections.

Pew's Kohut also warns that voters are wary after seeing the economy fail to achieve liftoff two and a half years after the Great Recession officially ended in June 2009. "The public is going to be in a show-me mood," he says.

Still, the online betting market Intrade on Friday put the chances of an Obama victory in November at 52.5 percent.

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20120108/ap_on_bi_ge/us_jobs_election

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Tiny worm points to big promise

Friday, January 6, 2012

Two related studies from Northwestern University offer new strategies for tackling the challenges of preventing and treating diseases of protein folding, such as Alzheimer's, Parkinson's and Huntington's diseases, amyotrophic lateral sclerosis (ALS), cancer, cystic fibrosis and type 2 diabetes.

To do its job properly within the cell, a protein first must fold itself into the proper shape. If it doesn't, trouble can result. More than 300 diseases have at their root proteins that misfold, aggregate and eventually cause cellular dysfunction and death.

The new Northwestern research identifies new genes and pathways that prevent protein misfolding and toxic aggregation, keeping cells healthy, and also identifies small molecules with therapeutic potential that restore health to damaged cells, providing new targets for drug development.

The genetic screening study is published by the journal PLoS Genetics. The small molecule study is published by the journal Nature Chemical Biology.

"These discoveries are exciting because we have identified genes that keep us healthy and small molecules that keep us healthy," said Richard I. Morimoto, who led the research. "Future research should explain how these two important areas interact."

Morimoto is the Bill and Gayle Cook Professor of Biology in the department of molecular biosciences and the Rice Institute for Biomedical Research in Northwestern's Weinberg College of Arts and Sciences. He also is a scientific director of the Chicago Biomedical Consortium.

The genetic study reported in PLoS Genetics was conducted in the transparent roundworm C. elegans, which shares much of the same biology with humans. The small animal is a valued research tool because of this and also because its genome, or complete genetic sequence, is known.

In the work, Morimoto and his team tested all of the approximately 19,000 genes in C. elegans. They reduced expression of each gene one at a time and looked to see if the gene suppressed protein aggregation in the cell. Did the gene increase aggregation or lessen it or have no effect at all?

The researchers found 150 genes that did have an effect. They then conducted a series of tests and zeroed in on nine genes that made all proteins in the cell healthier. (These genes had a positive effect on a number of different proteins associated with different diseases.)

These nine genes define a core homeostastis network that protects the animal's proteome (the entire set of proteins expressed by the organism) from protein damage. "These are the most important genes," Morimoto said. "Figuring out how nine genes -- as opposed to 150 -- work is a manageable task."

In the Nature Chemical Biology study, Morimoto and his colleagues screened nearly one million small molecules in human tissue culture cells to identify those that restore the cell's ability to protect itself from protein damage.

They identified seven classes of compounds (based on chemical structure) that all enhance the cell's ability to make more protective molecular chaperones, which restore proper protein folding. The researchers call these compounds proteostasis regulators. They found that the compounds restored the health of the cell and resulted in reduction of protein aggregation and protection against misfolding. Consequently, health was restored when diseased animals were treated with the small molecules.

Morimoto and his team then conducted detailed molecular analyses of 30 promising small molecules, representing all seven classes. They discovered some compounds were much more effective than others.

"We don't yet know the detailed mechanisms of these small molecules, but we have identified some good drug targets for further development," Morimoto said.

The PLoS Genetics paper, titled "A Genetic Screening Strategy Identifies Novel Regulators of the Proteostasis Network," is available at http://bit.ly/zzJNnm. M. Catarina Silva, a joint-doctoral student at Northwestern in the Morimoto lab and the University of Lisbon is the first author.

###

Northwestern University: http://www.northwestern.edu

Thanks to Northwestern University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/116525/Tiny_worm_points_to_big_promise

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Kelly Clarkson among 8 new "The Voice" guest-mentors (Reuters)

LOS ANGELES (TheWrap.com) ? Country star Miranda Lambert, Lionel Richie, Kelly Clarkson and five other big-name musical artists have signed on as guest mentors for the second season of NBC's "The Voice," the network said Friday.

Jewel, Alanis Morissette, Kenny "Babyface" Edmonds, Robin Thicke and Ne-Yo have also agreed to provide their expertise on the series, which returns with a special premiere following Super Bowl XLVI on February 5. (The season will begin in its regular time slot on Monday, February 6 from 8 to 10 p.m.)

Thicke and Morissette will mentor for members of Adam Levine's team, while Clarkson and Lambert will offer their services to Blake Shelton's team. Singers coached by Cee Lo Green will have Edmonds and Ne-Yo dispensing their wisdom, and Christina Aguilera's team will have Jewel and Richie on their side.

The guests will offer their services during the "battle rounds" of the series, which pits two artists from each team against each other to sing a duet.

The timing of Clarkson's inclusion on the series is particularly interesting. The "Breakaway" singer recently gained headlines (and probably a few enemies) with her endorsement of GOP presidential candidate Ron Paul. Clarkson, who's gearing up to tour in support of her most recent album "Stronger," will also serve as musical guest on the year's first new episode of NBC's "Saturday Night Live" this weekend.

"These renowned musicians will bring their unique and recognizable musical styles to the teams. They are well-respected singers whose invaluable experience will be a tremendous asset to Christina Aguilera, Cee Lo Green, Adam Levine and Blake Shelton's artists," Paul Telegdy, NBC's president, late night and alternative programming, said of the upcoming guests.

Reba McEntire, Sia, Adam Blackstone and Monica served as guest mentors on the show's inaugural season.

Javier Colon, from Adam Levine's team, won the first season of the series, which was adapted from the Dutch TV program "The Voice of Holland."

Source: http://us.rd.yahoo.com/dailynews/rss/tv/*http%3A//news.yahoo.com/s/nm/20120106/tv_nm/us_thevoice

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Kaz Hirai, Sony'nin Ba?kan? Oluyor

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Source: www.bolumsonucanavari.com --- Friday, January 06, 2012
Sony'nin en bilinen simalar?ndan biri olan Kaz Hirai, firman?n ba??na ge?meye haz?rlan?yor. ...

Source: http://www.bolumsonucanavari.com/Haberler-Kaz_Hirai_Sonynin_Baskani_Oluyor-23495.htm

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